Ep. 535 Masterclass: Inflammation, Hormones & Weight Loss
- Cynthia Thurlow
- Dec 31, 2025
- 2 min read
Today, we have the second episode of a two-part mashup series focused on weight-loss resistance.
For today’s episode, I am delighted to welcome experts Dr. Mary Claire Haver, Dr. Rocio Salas-Whalen, and Physician’s Assistant McCall McPherson.
Dr. Haver and I explore how inflammation drives weight gain and unpack specific strategies for macronutrients, meal timing, and more. Dr. Salas-Whalen and I examine body composition changes during perimenopause and menopause, our family responsibilities, the importance of strength training for maintaining muscle mass, and the targeted use of GLP-1 agonist drugs. Finally, McCall and I break down the labs that help guide decision-making, also discussing informed consent, the effects of hormonal replenishment therapy (now known as personalized endocrine treatment), the strategic use of GLP-1s, personalized dosages, and microdosing.
This mashup includes many timely and relevant insights from three experts at the forefront of women’s health. Join us as we explore the science, strategies, and solutions shaping the future of weight loss resistance.
IN THIS EPISODE, YOU WILL LEARN:
How slowing sugar absorption reduces insulin spikes and inflammation
The value of combining healthy fats, complex carbs, and lean protein at every meal
Why spreading protein intake throughout the day is crucial for metabolism, hormone regulation, and muscle preservation
How prioritizing self-care and modeling it for children helps break the cycle of parental over-sacrifice
Why strength training is more effective than cardio for long-term body composition and metabolic health
The mounting stress, family pressures, and reduced self-care that many women face in their 40s and 50s
How synthetic hormones in oral contraceptives disrupt thyroid, testosterone, and reproductive hormones
How GLP-1 agonists can improve weight loss, food freedom, and metabolic flexibility
How supporting adrenal health enhances energy, balances hormones, and improves metabolic flexibility
“There is a definite correlation between simple sugars and higher inflammation levels.”
– Dr. Mary Claire Haver
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Connect with Dr. Mary Claire Haver
On her website
Connect with Dr. Rocio Salas-Whalen
Connect with McCall McPherson
Transcript:
Dr. Mary Claire Haver's insights on sugar and inflammation, plus the talk on strength training, really make me question my habits; I definitely need to avoid any health 'strategies' that turn into gag recipes for my metabolism. After seeing this, maybe I'll ditch the scroll on the subway and plan my next workout instead, what a thought!
Test your reflexes in Geometry Dash, a rhythm platformer known for its difficulty, music sync, and precise mechanics.
Players must prioritize tasks to avoid falling behind papa's freezeria.
Slope Rider How prioritizing self-care and modeling it for children helps break the cycle of parental over-sacrifice
Wow, Dr. Haver really caught my attention when she mentioned the correlation between simple sugars and inflammation Z Image